Trial intelligence / Profile preview

Brexucabtagene Autoleucel in Rare B-cell Malignancies (ZUMA-25)

NCT05537766Phase 2Terminated

Sponsor
Kite Pharma
Start
Nov 2022
Primary completion
Jan 2025
Countries
8
01

Overview

Phase 2, open-label trial of brexucabtagene autoleucel in Waldenstrom macroglobulinemia (WM), Richter's syndrome (RS), Burkitt lymphoma (BL) and 1 more, sponsored by Kite Pharma. Primary endpoints: Combined Rate of Complete Response and Very Good Partial Response (Substudy A) at 2 years, Objective Response Rate (Substudy B) at 2 years and 2 more. Started Nov 2022; status: terminated.

02

Drugs

brexucabtagene autoleucel
03

Conditions

Waldenstrom macroglobulinemia (WM)Richter's syndrome (RS)Burkitt lymphoma (BL)hairy cell leukemia (HCL)

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