Trial intelligence / Profile preview

PF-07799544 in BRAF-Mutant Melanoma and Other Solid Tumors

NCT05538130Phase 1Active, not recruiting

Sponsor
Pfizer
Start
Nov 2022
Primary completion
Aug 2027
Modality
Small Molecules
Countries
7
01

Overview

Phase 1, open-label trial of polfurmetinib in melanoma, solid tumor, glioma and 2 more (3 arms), sponsored by Pfizer. Primary endpoints: Dose Limiting Toxicities at 21 days, Treatment-Emergent Adverse Events at 2 years and 4 more. Started Nov 2022; status: active, not recruiting.

02

Drugs

polfurmetinib
03

Conditions

melanomasolid tumorgliomathyroid cancernon-small cell lung cancer (NSCLC)

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