Trial intelligence / Profile preview

KFA115 as a Single Agent and in Combination With Pembrolizumab in Patients With Select Advanced Cancers

NCT05544929Phase 1Active, not recruiting

Sponsor
Novartis
Start
Oct 2022
Primary completion
Oct 2027
Modality
Small Molecules
Countries
12
01

Overview

Phase 1, open-label trial of KFA115 in non-small cell lung cancer (NSCLC), cutaneous melanoma (CM), renal cell carcinoma (RCC) and 9 more (3 arms), sponsored by Novartis. Primary endpoints: Dose Limiting Toxicities at 28 days, Adverse Events and Serious Adverse Events at 35 months and 2 more. Started Oct 2022; status: active, not recruiting.

02

Drugs

KFA115
03

Conditions

non-small cell lung cancer (NSCLC)cutaneous melanoma (CM)renal cell carcinoma (RCC)ovarian epithelial carcinomanasopharyngeal carcinoma (NPC)

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