Trial intelligence / Profile preview

Relative Bioavailability of Zanubrutinib Tablet vs Capsule and Food Effect

NCT05547399Phase 1Completed

Sponsor
BeiGene
Start
Jun 2022
Primary completion
Dec 2022
Modality
Fragment-Derived Small Molecules, Reversible Covalent Inhibitors, Bivalent/Multivalent Binders
Countries
1
01

Overview

Phase 1, randomised, open-label trial of zanubrutinib in B cell malignancies (2 cohorts), sponsored by BeiGene. Primary endpoints: Area under the plasma concentration-time curve from time 0 extrapolated to infinity, Area under the plasma concentration-time curve from time 0 to the time of the last quantifiable concentration and 5 more. Started Jun 2022; status: completed.

02

Drugs

zanubrutinib
03

Conditions

B cell malignancies

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