Trial intelligence / Profile preview

TACTIVE-U Sub-Study A: ARV-471 + Abemaciclib in ER+ Advanced/Metastatic Breast Cancer

NCT05548127Phase 2Active, not recruiting

Sponsor
Pfizer
Start
Feb 2023
Primary completion
Mar 2027
Modality
Bivalent/Multivalent Binders, PROTACs (E3 ligase recruitment)
Countries
4
01

Overview

Phase 2, open-label, single-arm trial of vepdegestrant in breast cancer, sponsored by Pfizer. Primary endpoints: Dose Limiting Toxicities at 28 days and Objective Response Rate at 1 year. Started Feb 2023; status: active, not recruiting.

02

Drugs

vepdegestrant
03

Conditions

breast cancer

Beyond the preview

Go deeper on NCT05548127.

Study design, results and competitive context are available in the Gosset platform where reported.

Study design & results

Available in the Gosset platform where reported.

Competitive context

Available in the Gosset platform where reported.

Bring the full picture into focus.

See how Gosset can support your research on NCT05548127.

Gosset Free

Get started with Gosset.

Enter your corporate email.

Work email preferred.

Book a call