Trial intelligence / Profile preview

DFV890 in Adult Patients With Myeloid Diseases

NCT05552469Phase 1Active, not recruiting

Sponsor
Novartis
Start
May 2023
Primary completion
Feb 2027
Modality
Small Molecules
Countries
8
01

Overview

Phase 1, randomised, open-label trial of DFV890 in myelodysplastic syndrome (MDS), chronic myelomonocytic leukemia (CMML) and clonal cytopenia of undetermined significance (CCUS) (3 arms), sponsored by Novartis. Primary endpoints: Incidence of Dose-limiting Toxicities at 28 days, Incidence and severity of Adverse Events and Serious Adverse Events at 36 months and 1 more. Started May 2023; status: active, not recruiting.

02

Drugs

DFV890
03

Conditions

myelodysplastic syndrome (MDS)chronic myelomonocytic leukemia (CMML)clonal cytopenia of undetermined significance (CCUS)

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