Trial intelligence / Profile preview

18F-Fluciclovine PET-MRI in Pediatric and Young Adult Low Grade Gliomas

NCT05555550Phase 1Recruiting

Sponsor
Children's Hospital of Philadelphia
Start
Nov 2026
Primary completion
Dec 2027
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of fluciclovine f 18 in glioma, sponsored by Children's Hospital of Philadelphia. Primary endpoints: Change in standardized uptake value parameters (SUVmax and SUVpeak) on metabolic tumor volume at 1 year and Changes in pretreatment tumor measurement on MRI at 1 year. Started Nov 2026; status: recruiting.

02

Drugs

fluciclovine f 18
03

Conditions

glioma

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