Trial intelligence / Profile preview

Safety and Efficacy of LYL845 in Advanced Solid Tumors

NCT05573035Phase 1Terminated

Sponsor
Lyell Immunopharma
Start
Dec 2022
Primary completion
Jan 2025
Modality
Tumor-Infiltrating Lymphocytes (TILs)
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of LYL845 in melanoma, non-small cell lung cancer (NSCLC) and colorectal cancer (CRC), sponsored by Lyell Immunopharma. Primary endpoints: Incidence of Dose-Limiting Toxicities at 28 days, Incidence of Treatment-Emergent Adverse Events at 2 years and 2 more. Started Dec 2022; status: terminated.

02

Drugs

LYL845
03

Conditions

melanomanon-small cell lung cancer (NSCLC)colorectal cancer (CRC)

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