Trial intelligence / Profile preview

Olpasiran in Atherosclerotic Cardiovascular Disease and Elevated Lipoprotein(a)

NCT05581303Phase 3Active, not recruiting

Sponsor
Amgen
Start
Dec 2022
Primary completion
Mar 2028
Modality
Conjugated siRNA, Chemically Modified siRNA
Countries
24
01

Overview

Phase 3, randomised, double-blind trial in atherosclerotic cardiovascular disease (ASCVD) comparing Placebo with Olpasiran (2 arms). Primary endpoint: Time to CHD death, myocardial infarction, or urgent coronary revascularization at 5 years. Started Dec 2022; status: active, not recruiting.

02

Drugs

olpasiran
03

Conditions

atherosclerotic cardiovascular disease (ASCVD)

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