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Pentoxifylline for chemotherapy-induced toxicities in colorectal cancer
NCT05590117Phase 1Unknown
- Sponsor
- Tanta University
- Start
- Oct 2022
- Primary completion
- Oct 2023
- Modality
- Small Molecules
- Countries
- 1
01
Overview
Phase 1, randomised, double-blind trial in chemotherapy-induced peripheral neuropathy (CIPN) and mucositis comparing Pentoxifylline Group with Placebo Group (2 arms). Primary endpoints: Percentage of patients with peripheral sensory neuropathy grade >= 2 at 6 months, Variation of 12-item neurotoxicity questionnaire (Ntx-12) total score at 6 months and 1 more. Status: unknown.
02
Drugs
pentoxifylline
03
Conditions
chemotherapy-induced peripheral neuropathy (CIPN)mucositis
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