Trial intelligence / Profile preview

IT-IO: Intrathecal Nivolumab and Ipilimumab for Leptomeningeal Metastasis

NCT05598853Phase 1Active, not recruiting

Sponsor
University of Zurich
Start
Nov 2022
Primary completion
Dec 2025
Modality
Monoclonal Antibodies
Countries
1
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Overview

Phase 1, open-label, single-arm trial of nivolumab and ipilimumab in leptomeningeal metastasis (LM), sponsored by University of Zurich. Primary endpoint: Recommended Phase II Dose at 3 weeks. Started Nov 2022; status: active, not recruiting.

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Drugs

nivolumabipilimumab
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Conditions

leptomeningeal metastasis (LM)

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