Trial intelligence / Profile preview

Minocycline In Neurocognitive Outcomes - Sickle Cell Disease

NCT05605366Phase 1Not yet recruiting

Sponsor
University of Cincinnati
Start
Dec 2026
Primary completion
Dec 2027
Modality
Small Molecules
01

Overview

Phase 1, randomised, double-blind trial of minocycline in sickle cell disease (SCD) and No canonical disease name; "cognitive deterioration" is a descriptive term, not a recognized disease entity (3 arms), sponsored by University of Cincinnati. Primary endpoint: Safety and tolerability of prolonged minocycline exposure at 12 months. Planned start Dec 2026; status: not yet recruiting.

02

Drugs

minocycline
03

Conditions

sickle cell disease (SCD)No canonical disease name; "cognitive deterioration" is a descriptive term, not a recognized disease entity.

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