Trial intelligence / Profile preview

Selpercatinib QTc interval study in healthy volunteers

NCT05630274Phase 1Completed

Sponsor
Eli Lilly and Company
Start
Apr 2019
Primary completion
Jun 2019
Modality
Fragment-Derived Small Molecules, Reversible Covalent Inhibitors, Bivalent/Multivalent Binders
Countries
1
01

Overview

Phase 1, randomised, double-blind trial of selpercatinib (4 arms), sponsored by Eli Lilly and Company. Primary endpoints: Placebo-corrected Change From Baseline in QT Interval Corrected Using Fridericia's Correction at 24 hours, Area Under the Concentration-time Curve From Time 0 to the Time of the Last Observed Non-zero Concentration at 240 hours and 6 more. Started Apr 2019; status: completed.

02

Drugs

selpercatinib

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