Trial intelligence / Profile preview

BMF-219 in KRAS-Mutated Advanced Solid Tumors

NCT05631574Phase 1Terminated

Sponsor
Biomea Fusion
Start
Jan 2023
Primary completion
Jan 2025
Modality
Covalent Small Molecules
Countries
2
01

Overview

Phase 1, open-label trial of icovamenib in non-small cell lung cancer (NSCLC), pancreatic cancer (PC) and colorectal cancer (CRC) (4 arms), sponsored by Biomea Fusion. Primary endpoint: Optimal Biologic Dose / Recommended Phase 2 Dose at 30 months. Started Jan 2023; status: terminated.

02

Drugs

icovamenib
03

Conditions

non-small cell lung cancer (NSCLC)pancreatic cancer (PC)colorectal cancer (CRC)

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