Trial intelligence / Profile preview

TP53-EphA-2-CAR-DC vaccine plus ICIs in advanced tumors

NCT05631886Phase 1Recruiting

Sponsor
Chinese PLA General Hospital
Start
Jul 2023
Primary completion
Dec 2025
Modality
Gene Editing, Whole Cell Cancer Vaccines, Gene Silencing
Countries
1
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Overview

Phase 1, open-label, single-arm trial of TP53-EphA-2-CAR-DC in solid tumor and lymphoma, sponsored by Chinese PLA General Hospital. Primary endpoints: Incidence of treatment related adverse events at 2 years, Clinical Response at 2 years and 1 more. Started Jul 2023; status: recruiting.

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Drugs

TP53-EphA-2-CAR-DC
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Conditions

solid tumorlymphoma

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