Trial intelligence / Profile preview

Consolidation Therapy Following CD19 CAR T-Cell Treatment for Relapsed/Refractory DLBCL or Grade IIIB FL

NCT05633615Phase 2Recruiting

Sponsor
SWOG Cancer Research Network
Start
Jun 2023
Primary completion
Jun 2030
Modality
Bispecific Antibodies, Antibody-Drug Conjugates (ADCs), Monoclonal Antibodies
Countries
1
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Overview

Phase 2, randomised, open-label trial of mosunetuzumab and polatuzumab vedotin in diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL) and primary mediastinal large B-cell lymphoma (PMBCL) (4 arms), sponsored by SWOG Cancer Research Network. Primary endpoint: Progression-Free Survival up to 2 years. Started Jun 2023; status: recruiting.

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Drugs

mosunetuzumabpolatuzumab vedotin
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Conditions

diffuse large B-cell lymphoma (DLBCL)follicular lymphoma (FL)primary mediastinal large B-cell lymphoma (PMBCL)

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