Trial intelligence / Profile preview

Effect of ARV-471 on Rosuvastatin PK in Healthy Participants

NCT05652660Phase 1Completed

Sponsor
Pfizer
Start
Dec 2022
Primary completion
Feb 2023
Modality
Bivalent/Multivalent Binders, PROTACs (E3 ligase recruitment)
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of vepdegestrant in breast cancer, sponsored by Pfizer. Primary endpoints: Maximum Plasma Concentration of Rosuvastatin and Area Under the Plasma Concentration-Time Profile From Time 0 to the Time of the Last Quantifiable Concentration of Rosuvastatin. Started Dec 2022; status: completed.

02

Drugs

vepdegestrant
03

Conditions

breast cancer

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