Trial intelligence / Profile preview

ADAPT: PK-based Hydroxyurea Dosing in Children With Sickle Cell Anemia

NCT05662098Phase 1Active, not recruiting

Sponsor
Cincinnati Children's Hospital Medical Center
Start
Jun 2022
Primary completion
Dec 2026
Modality
Small Molecules
Countries
1
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Overview

Phase 1, open-label, single-arm trial of hydroxyurea in sickle cell anemia (SCA), sponsored by Cincinnati Children's Hospital Medical Center. Primary endpoint: Rate of blood transfusions overall and by specific indications at 15 months. Started Jun 2022; status: active, not recruiting.

02

Drugs

hydroxyurea
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Conditions

sickle cell anemia (SCA)

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