Trial intelligence / Profile preview

PRT2527 in relapsed/refractory hematologic malignancies

NCT05665530Phase 1Completed

Sponsor
Prelude Therapeutics
Start
Sep 2023
Primary completion
Jun 2025
Modality
Orthosteric Ligands
Countries
10
01

Overview

Phase 1, open-label trial of PRT2527 in B-cell non-Hodgkin lymphoma (B-NHL), chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL) and 9 more (4 arms), sponsored by Prelude Therapeutics. Primary endpoints: Dose Limiting Toxicity at 35 days, Adverse Events at 2 years and 2 more. Started Sep 2023; status: completed.

02

Drugs

PRT2527
03

Conditions

B-cell non-Hodgkin lymphoma (B-NHL)chronic lymphocytic leukemia (CLL)small lymphocytic lymphoma (SLL)mantle cell lymphoma (MCL)Richter's syndrome (RS)

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