Trial intelligence / Profile preview

Niraparib/Abiraterone Acetate and Prednisone for mCRPC with SPOP Mutation

NCT05689021Phase 2Terminated

Sponsor
Mayo Clinic
Start
Mar 2024
Primary completion
Jul 2026
Modality
Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of niraparib + abiraterone acetate in castration-resistant prostate cancer (CRPC), sponsored by Mayo Clinic. Primary endpoint: Prostate Specific Antigen Response Rate at 13 months. Started Mar 2024; status: terminated.

02

Drugs

niraparib + abiraterone acetate
03

Conditions

castration-resistant prostate cancer (CRPC)

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