Trial intelligence / Profile preview

PBI-200 DDI Study with Ritonavir or Cobicistat in Healthy Volunteers

NCT05692570Phase 1Completed

Sponsor
Pyramid Biosciences
Start
Sep 2022
Primary completion
Nov 2022
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of paltimatrectinib in NTRK fusion-positive solid tumors, sponsored by Pyramid Biosciences. Primary endpoints: Maximum Plasma Concentration at 11 days, Area Under the Concentration-Time Curve from time zero to last measurable concentration at 11 days and 3 more. Started Sep 2022; status: completed.

02

Drugs

paltimatrectinib
03

Conditions

NTRK fusion-positive solid tumors

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