NTCD Colonisation in Healthy Volunteers

Phase 1, randomised, double-blind trial of nontoxigenic Clostridioides difficile strain M3 in Clostridioides difficile infection (CDI) (9 arms), sponsored by Leiden University Medical Center. Primary endpoints: Safety and tolerability of colonisation with non-toxigenic C.difficile at 1 month and Establish the effective protocol to obtain colonisation with non-toxigenic C. difficile at 1 month. Status: unknown.