Trial intelligence / Profile preview

DAA + Immunotherapy in HCC with HCV

NCT05717400Phase 4Terminated

Sponsor
University of Texas MD Anderson Cancer Center
Start
Mar 2023
Primary completion
Aug 2024
Modality
Reversible Covalent Inhibitors, Allosteric Modulators, Orthosteric Ligands
Countries
1
01

Overview

Phase 4, open-label, single-arm trial of sofosbuvir, velpatasvir and voxilaprevir in hepatocellular carcinoma (HCC) and chronic hepatitis C (CHC), sponsored by University of Texas MD Anderson Cancer Center. Primary endpoints: Overall Response Rate at 9 months, Sustained Virologic Response at 9 months and 1 more. Started Mar 2023; status: terminated.

02

Drugs

sofosbuvirvelpatasvirvoxilaprevir
03

Conditions

hepatocellular carcinoma (HCC)chronic hepatitis C (CHC)

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