Trial intelligence / Profile preview

AEO for Brain Radiation-Induced Metabolic Changes

NCT05720624Phase 1Withdrawn

Sponsor
Mayo Clinic
Start
Oct 2025
Primary completion
Oct 2025
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, randomised, open-label trial of oxaloacetate in malignant central nervous system neoplasm (4 cohorts), sponsored by Mayo Clinic. Primary endpoint: Feasibility of completing serial cerebrospinal fluid (CSF) collections for pharmacodynamic analyses at 3 months. Planned start Oct 2025; status: withdrawn.

02

Drugs

oxaloacetate
03

Conditions

malignant central nervous system neoplasm

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