Trial intelligence / Profile preview

Safety, Tolerability, and Pharmacokinetics of VX-668 in Healthy Volunteers

NCT05727800Phase 1Completed

Sponsor
Vertex Pharmaceuticals
Start
Feb 2023
Primary completion
Sep 2023
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, randomised, double-blind trial of VX-668 in alpha-1 antitrypsin deficiency (AATD) (4 arms), sponsored by Vertex Pharmaceuticals. Primary endpoint: Number of Participants With Adverse Events (AEs) and Serious Adverse Events (SAEs). Started Feb 2023; status: completed.

02

Drugs

VX-668
03

Conditions

alpha-1 antitrypsin deficiency (AATD)

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