Trial intelligence / Profile preview

Neoadjuvant Pembrolizumab +/- Lenvatinib for High Risk Renal Cell Carcinoma

NCT05733715Phase 1Recruiting

Sponsor
Abramson Cancer Center
Start
May 2023
Primary completion
Apr 2028
Modality
Immune Checkpoint Inhibitors, Recombinant Proteins and Enzymes, Small Molecules
Countries
1
01

Overview

Phase 1, randomised, open-label trial in renal cell carcinoma (RCC) comparing Pembrolizumab + Lenvatinib with Pembrolizumab (2 arms). Primary endpoint: Change in frequency of progenitor exhausted CD8 T cells. Started May 2023; status: recruiting.

02

Drugs

pembrolizumablenvatinib
03

Conditions

renal cell carcinoma (RCC)

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