Trial intelligence / Profile preview

MRTX1133 in KRAS G12D+ Advanced Solid Tumors

NCT05737706Phase 1Terminated

Sponsor
Mirati Therapeutics
Start
Mar 2023
Primary completion
Mar 2025
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, open-label trial of MRTX1133 in solid tumor (advanced stage), non-small cell lung cancer (NSCLC), colorectal cancer (CRC) and 1 more (2 arms), sponsored by Mirati Therapeutics. Primary endpoints: Number of Patients who Experience Dose-Limiting Toxicity at 21 Days, Number of patients who experience a treatment-related adverse event up to 2 years and 4 more. Started Mar 2023; status: terminated.

02

Drugs

MRTX1133
03

Conditions

solid tumor (advanced stage)non-small cell lung cancer (NSCLC)colorectal cancer (CRC)pancreatic adenocarcinoma (PDAC)

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