Trial intelligence / Profile preview

Pozelimab and Cemdisiran Combination Therapy in PNH

NCT05744921Phase 3Recruiting

Sponsor
Regeneron Pharmaceuticals
Start
Mar 2023
Primary completion
Oct 2028
Modality
Antisense DNA, Recombinant Proteins and Enzymes, Conjugated siRNA
Countries
20
01

Overview

Phase 3, open-label trial of pozelimab and cemdisiran in paroxysmal nocturnal hemoglobinuria (PNH) (2 arms), sponsored by Regeneron Pharmaceuticals. Primary endpoints: Incidence of treatment-emergent serious adverse events, Severity of treatment-emergent serious adverse events and 5 more. Started Mar 2023; status: recruiting.

02

Drugs

pozelimabcemdisiran
03

Conditions

paroxysmal nocturnal hemoglobinuria (PNH)

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