Trial intelligence / Profile preview

AOC 1020 in Facioscapulohumeral Muscular Dystrophy (FSHD)

NCT05747924Phase 2Completed

Sponsor
Avidity Biosciences
Start
Apr 2023
Primary completion
Mar 2026
Modality
Antisense DNA, Antibody-Drug Conjugates (ADCs), Conjugated siRNA
Countries
3
01

Overview

Phase 2, randomised, double-blind trial of delpacibart braxlosiran in facioscapulohumeral muscular dystrophy (FSHD) (5 arms), sponsored by Avidity Biosciences. Primary endpoints: Incidence of treatment-emergent adverse events at Day 365 and Change in plasma KHDC1L at Month 12. Started Apr 2023; status: completed.

02

Drugs

delpacibart braxlosiran
03

Conditions

facioscapulohumeral muscular dystrophy (FSHD)

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