Trial intelligence / Profile preview

Mitiperstat PK in Hepatic Impairment

NCT05751759Phase 1Completed

Sponsor
AstraZeneca
Start
Mar 2023
Primary completion
Nov 2024
Modality
Small Molecules
Countries
1
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Overview

Phase 1, open-label trial of mitiperstat in heart failure with preserved ejection fraction (HFpEF), chronic obstructive pulmonary disease (COPD) and Nonalcoholic steatohepatitis (NASH) (4 arms), sponsored by AstraZeneca. Primary endpoints: Maximum Observed Plasma Concentration, Area Under the Concentration-Time Curve from Time Zero to Infinity and 7 more. Started Mar 2023; status: completed.

02

Drugs

mitiperstat
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Conditions

heart failure with preserved ejection fraction (HFpEF)chronic obstructive pulmonary disease (COPD)Nonalcoholic steatohepatitis (NASH)

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