Trial intelligence / Profile preview

Mechanisms of Diuretic Resistance in Heart Failure, Aim 2

NCT05753059Phase 1Recruiting

Sponsor
Yale University
Start
Aug 2023
Primary completion
Jun 2028
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, randomised, double-blind trial of bendroflumethiazide and amiloride in heart failure (HF) (4 arms), sponsored by Yale University. Primary endpoints: Change in peak fractional excretion of sodium at 21 days, Change in distal sodium reabsorption at 21 days and 1 more. Started Aug 2023; status: recruiting.

02

Drugs

bendroflumethiazideamiloride
03

Conditions

heart failure (HF)

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