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Focused Ultrasound With Oral Etoposide in Children With Progressive Diffuse Midline Glioma
NCT05762419Phase 1Recruiting
- Sponsor
- Columbia University
- Start
- Jun 2023
- Primary completion
- Dec 2026
- Modality
- Small Molecules
- Countries
- 1
01
Overview
Phase 1, open-label, single-arm trial of etoposide in diffuse midline glioma (DMG) and diffuse intrinsic pontine glioma (DIPG), sponsored by Columbia University. Primary endpoints: Number of total adverse events at 90 days and Number of patients with successful opening of the blood brain barrier. Started Jun 2023; status: recruiting.
02
Drugs
etoposide
03
Conditions
diffuse midline glioma (DMG)diffuse intrinsic pontine glioma (DIPG)
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