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Naloxegol for Opioid-Induced Colonic Motor Pattern Changes in Healthy Volunteers
NCT05770960Phase 4Completed
- Sponsor
- UZ Leuven
- Start
- Jun 2018
- Primary completion
- May 2019
- Modality
- Metabolically Activated Prodrugs
- Countries
- 1
01
Overview
Phase 4, randomised, double-blind trial in opioid-induced constipation (OIC) comparing Naloxegol + Codeine, Placebo + Codeine and Naloxegol + Placebo (3 arms). Primary endpoint: Prevalence of anterograde colonic motor patterns at 6 hours. Started Jun 2018; status: completed.
02
Drugs
naloxegol
03
Conditions
opioid-induced constipation (OIC)
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