Trial intelligence / Profile preview

JANX008 in Advanced or Metastatic Solid Tumors

NCT05783622Phase 1Active, not recruiting

Sponsor
Janux Therapeutics
Start
Apr 2023
Primary completion
Jul 2026
Modality
Bispecific Antibodies, Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 1, open-label trial of JANX008 in non-small cell lung cancer (NSCLC), renal cell carcinoma (RCC), squamous cell carcinoma of the head and neck (HNSCC) and 4 more (3 arms), sponsored by Janux Therapeutics. Primary endpoints: Incidence of Dose Limiting Toxicities at 21 days, Incidence of Adverse Events and Serious Adverse Events up to 4 years and 1 more. Started Apr 2023; status: active, not recruiting.

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Drugs

JANX008
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Conditions

non-small cell lung cancer (NSCLC)renal cell carcinoma (RCC)squamous cell carcinoma of the head and neck (HNSCC)colorectal carcinoma (CRC)small cell lung cancer (SCLC)

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