Trial intelligence / Profile preview

Anti-CD19 and Anti-CD20 CAR T-Cells in B-cell Malignancies

NCT05797233Phase 1Active, not recruiting

Sponsor
National Cancer Institute
Start
Aug 2023
Primary completion
Dec 2028
Modality
Gene Editing, Gene Silencing, CAR-T Cells
Countries
1
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Overview

Phase 1, open-label trial of Hu1928-Hu20BB-Long in B cell lymphoma, chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) (2 arms), sponsored by National Cancer Institute. Primary endpoint: Safety and Feasibility of Administering CAR T-cells at 30 days. Started Aug 2023; status: active, not recruiting.

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Drugs

Hu1928-Hu20BB-Long
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Conditions

B cell lymphomachronic lymphocytic leukemia (CLL)small lymphocytic lymphoma (SLL)

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