Trial intelligence / Profile preview

PanACEA-STEP2C-01: Novel and Optimized Regimens for Pulmonary TB

NCT05807399Phase 2Recruiting

Start
Apr 2023
Primary completion
Oct 2027
Modality
Irreversible Covalent Inhibitors, Metabolically Activated Prodrugs
Countries
6
01

Overview

Phase 2, randomised, open-label trial of BTZ-043, alpibectir, ganfeborole and delpazolid in pulmonary tuberculosis (TB) (7 arms). Primary endpoints: Time to stable culture conversion to negative in liquid media and Change in Mycobacterial load. Started Apr 2023; status: recruiting.

02

Drugs

BTZ-043alpibectirganfeboroledelpazolid
03

Conditions

pulmonary tuberculosis (TB)

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