Trial intelligence / Profile preview

SOLSTICE: Vericiguat in Cardiac Surgery

NCT05812755Phase 4Recruiting

Sponsor
Vanderbilt University Medical Center
Start
May 2023
Primary completion
Jul 2028
Modality
Small Molecules
Countries
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Overview

Phase 4, randomised trial of Vericiguat oral suspension (Formulation 4) in acute kidney injury (AKI), traumatic brain injury (TBI) and endothelial dysfunction (2 arms), sponsored by Vanderbilt University Medical Center. Primary endpoints: Brachial artery flow-mediated dilation, Ex vivo vascular relaxation and 2 more. Started May 2023; status: recruiting.

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Drugs

Vericiguat oral suspension (Formulation 4)
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Conditions

acute kidney injury (AKI)traumatic brain injury (TBI)endothelial dysfunction

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