Trial intelligence / Profile preview

CD19 CAR-T in Refractory Myasthenia Gravis

NCT05828225Phase 1Recruiting

Sponsor
Zhejiang University
Start
Apr 2023
Primary completion
Apr 2026
Modality
Gene Editing, Gene Silencing, CAR-T Cells
Countries
1
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Overview

Phase 1, open-label, single-arm trial of Autologous CD19 CAR-T (Institute of Hematology & Blood Diseases Hospital) in myasthenia gravis (MG), sponsored by Zhejiang University. Primary endpoints: Dose-limiting toxicity at 28 days, Treatment-emergent adverse events at 90 days and 1 more. Started Apr 2023; status: recruiting.

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Drugs

Autologous CD19 CAR-T (Institute of Hematology & Blood Diseases Hospital)
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Conditions

myasthenia gravis (MG)

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