Trial intelligence / Profile preview

Intra-Tumoral Injections of Ex Vivo Expanded Natural Killer Cells in Recurrent or Progressive Malignant Brain Tumors

NCT05887882Phase 1Suspended

Start
May 2024
Primary completion
Dec 2027
Modality
Lymphokine-Activated Killer Cells, CAR-NK Cells
Countries
1
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Overview

Phase 1, open-label trial of transforming growth factor-beta-imprinted natural killer cells in brain tumor (3 arms). Primary endpoints: Proportion of participants with treatment-emergent adverse events at 1 year and Recommended Phase II dose at 1 year. Started May 2024; status: suspended.

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Drugs

transforming growth factor-beta-imprinted natural killer cells
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Conditions

brain tumor

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