Trial intelligence / Profile preview

Tafasitamab-Based Therapy with Targeted Agents in R/R LBCL

NCT05890352Phase 2Recruiting

Sponsor
SWOG Cancer Research Network
Start
Sep 2023
Primary completion
Dec 2029
Modality
Fragment-Derived Small Molecules, Reversible Covalent Inhibitors, Bivalent/Multivalent Binders
Countries
1
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Overview

Phase 2, randomised, open-label trial of tazemetostat and zanubrutinib in diffuse large B-cell lymphoma (DLBCL) (5 arms), sponsored by SWOG Cancer Research Network. Primary endpoints: Progression-Free Survival at 3 years and Functional Assessment of Cancer Therapy-Lymphoma Trial Outcome Index at 3 months. Started Sep 2023; status: recruiting.

02

Drugs

tazemetostatzanubrutinib
03

Conditions

diffuse large B-cell lymphoma (DLBCL)

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