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Pembrolizumab + Belzutifan + Lenvatinib or Pembrolizumab/Quavonlimab + Lenvatinib vs Pembrolizumab + Lenvatinib in Advanced ccRCC

NCT05899049Phase 3Active, not recruiting

Sponsor
Merck & Co.
Start
Jul 2022
Primary completion
Feb 2026
Modality
Small Molecules, Monoclonal Antibodies
Countries
1
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Overview

Phase 3, randomised, open-label trial of belzutifan and pembrolizumab + quavonlimab in clear cell renal cell carcinoma (ccRCC) (3 arms), sponsored by Merck & Co. Primary endpoints: Progression-Free Survival and Overall Survival. Started Jul 2022; status: active, not recruiting.

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Drugs

belzutifanpembrolizumab + quavonlimab
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Conditions

clear cell renal cell carcinoma (ccRCC)

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