Trial intelligence / Profile preview

VLS-1488 in advanced solid tumors

NCT05902988Phase 2Recruiting

Sponsor
Volastra Therapeutics
Start
Oct 2023
Primary completion
Jun 2026
Modality
Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial of VLS-1488 in High-Grade Serous Ovarian Carcinoma (HGSOC), squamous cell carcinoma of the lung (SCCL), triple-negative breast cancer (TNBC) and 11 more (4 arms), sponsored by Volastra Therapeutics. Primary endpoints: Dose Limiting Toxicities at 12 months, Maximum Tolerated Dose at 12 months and 6 more. Started Oct 2023; status: recruiting.

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Drugs

VLS-1488
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Conditions

High-Grade Serous Ovarian Carcinoma (HGSOC)squamous cell carcinoma of the lung (SCCL)triple-negative breast cancer (TNBC)gastric adenocarcinomacolorectal cancer (CRC)

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