Trial intelligence / Profile preview

Selpercatinib DDI Study with Rosuvastatin in Healthy Participants

NCT05906836Phase 1Completed

Sponsor
Eli Lilly and Company
Start
Jul 2023
Primary completion
Oct 2023
Modality
Fragment-Derived Small Molecules, Reversible Covalent Inhibitors, Bivalent/Multivalent Binders
Countries
1
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Overview

Phase 1, open-label, single-arm trial of selpercatinib in non-small cell lung cancer (NSCLC), Medullary Thyroid Cancer (MTC), thyroid cancer and 1 more, sponsored by Eli Lilly and Company. Primary endpoints: Maximum Concentration of Rosuvastatin at Day 5 and Area Under the Concentration Versus Time Curve From Time Zero to Infinity of Rosuvastatin at Day 5. Started Jul 2023; status: completed.

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Drugs

selpercatinib
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Conditions

non-small cell lung cancer (NSCLC)Medullary Thyroid Cancer (MTC)thyroid cancersolid tumor

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