Trial intelligence / Profile preview

TOKOMEZA: Sudan Ebolavirus Vaccines

NCT05909358Phase 2Not yet recruiting

Sponsor
Makerere University
Start
Jul 2023
Primary completion
Sep 2027
Modality
Recombinant Proteins and Enzymes, DNA Vaccines, Live Vector Vaccines
01

Overview

Phase 2, randomised, double-blind trial of cAd3-EBO S, ChAdOx1 biEBOV and Sudan ebolavirus vaccine in Sudan virus disease (SVD) (4 arms), sponsored by Makerere University. Primary endpoints: Incidence of solicited, unsolicited adverse and serious adverse events at 72 months, Vaccine-specific antibody concentration at 72 months and 2 more. Planned start Jul 2023; status: not yet recruiting.

02

Drugs

cAd3-EBO SChAdOx1 biEBOVSudan ebolavirus vaccine
03

Conditions

Sudan virus disease (SVD)

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