Trial intelligence / Profile preview

Crizanlizumab +/- Nivolumab for Glioblastoma and Melanoma Brain Metastases

NCT05909618Phase 2Recruiting

Sponsor
Sheba Medical Center
Start
Jul 2023
Primary completion
Jul 2028
Modality
Monoclonal Antibodies
Countries
1
01

Overview

Phase 2, open-label trial of crizanlizumab in glioblastoma (GBM) and melanoma (3 arms), sponsored by Sheba Medical Center. Primary endpoints: Incidence of treatment-related adverse events and serious adverse events at 48 months and Proportion of treatment discontinuation events at 48 months. Started Jul 2023; status: recruiting.

02

Drugs

crizanlizumab
03

Conditions

glioblastoma (GBM)melanoma

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