Trial intelligence / Profile preview

Aficamten QT/QTc Study in Healthy Participants

NCT05924815Phase 1Completed

Sponsor
Cytokinetics
Start
May 2023
Primary completion
Nov 2023
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, randomised, double-blind trial of aficamten in hypertrophic cardiomyopathy (HCM) (6 arms), sponsored by Cytokinetics. Primary endpoints: Dose determination for Part B at 8 weeks and Placebo-corrected change from baseline in QTcF at 14.5 weeks. Started May 2023; status: completed.

02

Drugs

aficamten
03

Conditions

hypertrophic cardiomyopathy (HCM)

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