Trial intelligence / Profile preview

CHEM-FACT: Anesthesia and Vasopressors in Adult Surgery

NCT05941494Phase 4Recruiting

Start
Oct 2023
Primary completion
Dec 2025
Modality
Small Molecules
Countries
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Overview

Phase 4, randomised, single-blind trial of propofol injection (veterinary), sevoflurane, phenylephrine and ephedrine in general anesthesia and intraoperative hypotension (IOH) (4 arms). Primary endpoint: Effects of anesthetic maintenance agents and vasopressors on cerebral hemodynamics and metabolism. Started Oct 2023; status: recruiting.

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Drugs

propofol injection (veterinary)sevofluranephenylephrineephedrine
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Conditions

general anesthesiaintraoperative hypotension (IOH)

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