Trial intelligence / Profile preview

Mitoxantrone Liposome Combinations in De Novo AML

NCT05941585Completed

Sponsor
Institute of Hematology and Blood Diseases Hospital
Start
Aug 2023
Primary completion
Jan 2025
Modality
Lipid-based Nanoparticles, CAR-T Cells, Small Molecules
Countries
1
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Overview

Randomised, open-label trial of mitoxantrone hydrochloride liposome injection + fludarabine + CD19 CAR-T cells in acute myeloid leukemia (AML) (3 arms), sponsored by Institute of Hematology and Blood Diseases Hospital. Primary endpoint: Treatment-Emergent Adverse Events at 1 month. Started Aug 2023; status: completed.

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Drugs

mitoxantrone hydrochloride liposome injection + fludarabine + CD19 CAR-T cells
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Conditions

acute myeloid leukemia (AML)

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