Trial intelligence / Profile preview

IMC002 in CLDN18.2-positive Advanced Digestive System Tumors

NCT05946226Phase 1Recruiting

Sponsor
Immunofoco
Start
Sep 2023
Primary completion
Dec 2025
Modality
Prophylactic Vaccines, Therapeutic Vaccines, Monoclonal Antibodies
Countries
1
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Overview

Phase 1, open-label, single-arm trial of claudin 18.2 CAR-T in gastric cancer (GC), esophagogastric junction adenocarcinoma (GEJA), pancreatic cancer (PC) and 1 more, sponsored by Immunofoco. Primary endpoint: Incidence and severity of dose-limiting toxicity at 28 days. Started Sep 2023; status: recruiting.

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Drugs

claudin 18.2 CAR-T
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Conditions

gastric cancer (GC)esophagogastric junction adenocarcinoma (GEJA)pancreatic cancer (PC)digestive system neoplasms

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