Trial intelligence / Profile preview

Acoziborole DDI Study with Midazolam and Dextromethorphan

NCT05947604Phase 1Completed

Sponsor
Drugs for Neglected Diseases initiative
Start
Feb 2023
Primary completion
May 2023
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of acoziborole in African trypanosomiasis (HAT), sponsored by Drugs for Neglected Diseases initiative. Primary endpoints: Maximum Plasma Concentration (Cmax) of Midazolam, Maximum Plasma Concentration (Cmax) of Dextromethorphan and 4 more. Started Feb 2023; status: completed.

02

Drugs

acoziborole
03

Conditions

African trypanosomiasis (HAT)

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